Figure 3.

MIR-Exposed Mice Display Autism-Associated Deficits in Behaviors

(A) Mean duration of ultrasonic vocalizations by P7 pups when separated from the dam.

(B) Mean percent total time spent in each condition in the three-chamber social interaction test.

(C) Mean percent total time spent in each maze location and the latency to enter open arms in the elevated plus maze test.

(D) Correlation between brain size and repetitive grooming behavior. Data shown were obtained from each pup from two litters.

(E) Average weight gain in control and treated animals over 14 postnatal days.

(F) Average total path length traveled during the three-chamber social interaction test. n = 16 mice per group; ^∗p < 0.05. All data are presented as mean ± SEM.