Table 1.
Number of genes encoding ZNP network proteins and number of total genes modulated in inflamed and non-inflamed tissue from CD patients
Parallels | Modulated ZNP | Modulated genes | Hypergeometric distribution (ZNP MA vs. ZNP in genome) p value |
---|---|---|---|
1. Inflamed CD versus non-inflamed CD | 152 | 382 | 0.003 |
2. Non-inflamed CD versus control | 179 | 511 | 0.56 |
3. CD versus control terminal ileum | 591 | 1,667 | 0.49 |
4. Inflamed CD versus control | 87 | 311 | 0.99 |
The p values listed in the last column were estimated by hypergeometric distribution and express the likelihood that ZNP network genes might be overrepresented within the modulated expression profiles compared to their occurrence within the human genome