Skip to main content
. 2014 Aug 2;5(3):242–245. doi: 10.1007/s13193-014-0342-3

Table 1.

Histopathological characteristics of the common differential diagnosis of mesenteric fibromatosis

Differential diagnosis Gross features Histopathological features Immunohistopathological features
Mesentric fibromatosis Tan gray masses with infiltrative margins and homogenous parenchyma without any hemorrhagic, cystic or necrotic changes Monotonous spindle cells growing in long, sweeping fascicles Minimal or complete absence of mitotic activity Vimentin, B-catenin positive, negative for CD34,c-kit
Solitary fibrous tumor Well defined masses with firm, pale cut surface showing whorled fibrous tissue. Scarce cellularity increase vascularity. showing hyalanization. CD34, CD99 and Bcl-2 positive
GIST Expansive,firm, pale multilobulated soft masses associated with areas hemorrhagic, cystic and necrotic changes Spindle and epitheloid cells with organoid cellular arrangement. Varying degree of mitosis present with or without atypia. c-kit CD117,CD34 positive, negative for beta catenin
Inflammatory Myofibroblastic tumour. Non encapsulated, circumscribed nodular masses with occasional infiltrative margins Increased cellularity with predominance of inflammatory cells and myofibroblasic proliferation Activin like kinase positive, beta catenin negative.