Mesentric fibromatosis |
Tan gray masses with infiltrative margins and homogenous parenchyma without any hemorrhagic, cystic or necrotic changes |
Monotonous spindle cells growing in long, sweeping fascicles Minimal or complete absence of mitotic activity |
Vimentin, B-catenin positive, negative for CD34,c-kit |
Solitary fibrous tumor |
Well defined masses with firm, pale cut surface showing whorled fibrous tissue. |
Scarce cellularity increase vascularity. showing hyalanization. |
CD34, CD99 and Bcl-2 positive |
GIST |
Expansive,firm, pale multilobulated soft masses associated with areas hemorrhagic, cystic and necrotic changes |
Spindle and epitheloid cells with organoid cellular arrangement. Varying degree of mitosis present with or without atypia. |
c-kit CD117,CD34 positive, negative for beta catenin |
Inflammatory Myofibroblastic tumour. |
Non encapsulated, circumscribed nodular masses with occasional infiltrative margins |
Increased cellularity with predominance of inflammatory cells and myofibroblasic proliferation |
Activin like kinase positive, beta catenin negative. |