Effect of A. bidentata extract (AE) on the differentiation of MC3T3-E1 cells. The measured values are converted to % of control group. The control values for a collagen content, b ALP activity, c osteocalcin, and d mineralization were 23.45 ± 0.659 μg/106 cells, 0.871 ± 0.016 Unit/mg protein, 42.09 ± 1.958 ng/mg protein, and 0.504 ± 0.006 OD/106 cells, respectively. *P < 0.05 compared with control