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Effect of A. bidentata extract (AE) on the CREB phosphorylation of osteoblastic MC3T3-E1 cells in the presence of antimycin A. Osteoblasts were treated with AE in the presence of 70 μM antimycin A (AMA) for 48 h. Data are expressed as percentage of the control. The control values for phosphorylated CREB was 0.46 ± 0.026 phospho-CREB/total CREB. *P < 0.05; control versus AMA, # P < 0.05; AMA versus AE
