Table 1. Summary of DNA methylation, mRNA and protein expression changes of SFRP1 gene and protein in the stromal compartment.

	analyzed cells	NAT	Tumor	P
mRNA expression	stroma (LCM)	logFCCRC-N = −2.23		<0.001
		n = 38	n = 38
DNA methylation	α-SMA myofibroblasts (LCM)	0%	60%	n.a.
		n = 3/3	n = 3/3
protein expression	α-SMA+ SFRP1+/α-SMA cells (LCM)	85.37%±12.6%	27.65%±18.2%	<0.001
		n = 9/9	n = 9/9

LCM: laser capture microdissection.