Table 4.
Final rAAV8 Reference Standard Material Titer Estimates After Transformation and Modeling
Titer units | Transformation | Mean | Lower 95% confidence limit for the mean | Upper 95% confidence limit for the mean | ±2 SD |
---|---|---|---|---|---|
Particles (pt)/ml | None | 5.5×1011 | 4.26×1011 | 6.75×1011 | 1.06×1011 to 9.94×1011 |
Vector genomes (vg)/ml | Log10 | 5.75×1011 | 3.05×1011 | 1.09×1012 | 4.57×1010 to 7.24×1012 |
Infectious units (IU)/ml | Log10 | 1.26×109 | 6.46×108 | 2.51×109 | 1.32×108 to 1.20×1010 |