Table 3. Co-infection of HPV and EBV in head and neck cancers, according to PCR for HPV DNA and ISH for EBER.

		EBER positive	EBER negative	P value
		n (%)
HNC	HPV positive	2 (1.0)	61 (29.2)	0.352
	HPV negative	11 (5.2)	135 (64.6)
NPC	HPV positive	2 (10.0)	4 (20.0)	0.161
	HPV negative	10 (50.0)	4 (20.0)

HPV, human papillomavirus; EBV, Epstein-Barr virus; PCR, polymerase chain reaction; ISH, in situ hybridization; HNC, head and neck cancer; NPC, nasopharyngeal cancer; EBER, Epstein-Barr virus encoded RNA.