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. 2014 Nov 18;9(11):e113513. doi: 10.1371/journal.pone.0113513

Table 1. Baseline characteristics of the phase I cohort.

Variables n %
Sex
Male 150 53.6
Female 130 46.4
Age at diagnosis
Median 68.42 years (range:25.29–91.61)
Grade
Poorly differentiated/undifferentiated 42 15
Well/moderately differentiated 234 83.6
Unknown 4 1.4
Histology
Mucinous 43 15.4
Non-mucinous 237 84.6
Location
Rectum 57 20.4
Colon 223 79.6
Lymphatic invasion of tumor
Lymphatic invasion (+) 110 39.3
Lymphatic invasion (−) 70 25
Unknown 100 35.7
Stage
I 54 19.3
II 94 33.6
III 76 27.1
IV 47 16.8
Unknown 9 3.2
MSI status
MSI-H 34 12.1
MSS/MSI-L 246 87.9
Prognostic and follow up information
OS status at the time of last follow up
Dead 172 61.4
Alive 108 38.6
Median OS and DSS (follow up) time 5.31 years (range: 0–12.52)
DFS status at the time of last follow up
Recurrence/metastasis/death (+) 184 65.7
Recurrence/metastasis/death (−) 96 34.3
DFS (follow up) time 3.37 years (range: 0–12.52)
DSS status at the time of last follow up
Death from colorectal cancer 113 40.4
Death from other causes or alive 167 59.6

(+): present, (−): absent, DFS: disease free survival, DSS: disease specific survival, MSI-H: microsatellite instability-high, MSI-L: microsatellite instability-low, MSS: microsatellite stable, OS: overall survival.