Table 1. Baseline characteristics of the phase I cohort.
Variables | n | % |
Sex | ||
Male | 150 | 53.6 |
Female | 130 | 46.4 |
Age at diagnosis | ||
Median | 68.42 years (range:25.29–91.61) | |
Grade | ||
Poorly differentiated/undifferentiated | 42 | 15 |
Well/moderately differentiated | 234 | 83.6 |
Unknown | 4 | 1.4 |
Histology | ||
Mucinous | 43 | 15.4 |
Non-mucinous | 237 | 84.6 |
Location | ||
Rectum | 57 | 20.4 |
Colon | 223 | 79.6 |
Lymphatic invasion of tumor | ||
Lymphatic invasion (+) | 110 | 39.3 |
Lymphatic invasion (−) | 70 | 25 |
Unknown | 100 | 35.7 |
Stage | ||
I | 54 | 19.3 |
II | 94 | 33.6 |
III | 76 | 27.1 |
IV | 47 | 16.8 |
Unknown | 9 | 3.2 |
MSI status | ||
MSI-H | 34 | 12.1 |
MSS/MSI-L | 246 | 87.9 |
Prognostic and follow up information | ||
OS status at the time of last follow up | ||
Dead | 172 | 61.4 |
Alive | 108 | 38.6 |
Median OS and DSS (follow up) time | 5.31 years (range: 0–12.52) | |
DFS status at the time of last follow up | ||
Recurrence/metastasis/death (+) | 184 | 65.7 |
Recurrence/metastasis/death (−) | 96 | 34.3 |
DFS (follow up) time | 3.37 years (range: 0–12.52) | |
DSS status at the time of last follow up | ||
Death from colorectal cancer | 113 | 40.4 |
Death from other causes or alive | 167 | 59.6 |
(+): present, (−): absent, DFS: disease free survival, DSS: disease specific survival, MSI-H: microsatellite instability-high, MSI-L: microsatellite instability-low, MSS: microsatellite stable, OS: overall survival.