Table 1. ORNs used in this study and their efficiency of suppression in ORNi-PCR.
Number | Name | ORN sequence (5′–3′) | Length(base) | IC50 (nM) | Experiments |
R4 | ORN-302F | ccgggggcgcugggcuguccc | 21 | 14.86 | Figures 1D and 3B |
R6 | ORN-298F | gggcgcugggcuguccc | 17 | 77.64 | Figure 1E |
R5 | ORN-306F | ggggccgggggcgcugggcuguccc | 25 | 6.415 | Figure 1F |
14.76 | Figure 1I | ||||
R7 | ORN-310F | ggcuggggccgggggcgcugggcuguccc | 29 | 9.236 | Figure 1G |
R10 | ORN-666R | ggccgcugcuggcacagcccc | 21 | 12.01 | Figure 2B |
R9 | ORN-363R | cacccuccuggcggggcgggg | 21 | 10.63 | Figures 2C and 3B |
R8 | ORN-181R | cacccucuccggccgggcgcc | 21 | 34.52 | Figure 2D |
R11 | ORN-MCS | agagcggccgccaccgcggug | 21 | 674.5 | Figure 4B |
604.4 | Figure 4C | ||||
229.0 | Figure 5B | ||||
204.2 | Figure 6B | ||||
526.7 | Figure 6B |