Table 1.
Genes with functional AT-associated methylationa
| Gene symbol | p* | Chromosome | Gene name |
|---|---|---|---|
| PIK3R1 | 0.00215 | 5 | Phosphoinositide-3-kinase, regulatory subunit 1 (α) |
| KLHDC9 | 0.00232 | 1 | kelch domain containing 9 |
| JAG1 | 0.00312 | 20 | jagged 1 |
| URM1 | 0.00363 | 9 | Ubiquitin-related modifier 1 |
| SHKBP1 | 0.00395 | 19 | SH3KBP1 binding protein 1 |
| ZNF521 | 0.00796 | 18 | Zinc finger protein 521 |
| GRIN1 | 0.00823 | 9 | Glutamate receptor, ionotropic, N-methyl-d-aspartate 1 |
| PIP5K1B | 0.01401 | 9 | Phosphatidylinositol-4-phosphate 5-kinase, Type I, β |
| ERC2 | 0.01435 | 3 | ELKS/RAB6-interacting/CAST family member 2 |
| ABCB1 | 0.01504 | 7 | ATP-binding cassette, subfamily B (MDR/TAP), member 1 |
| SCAMP3 | 0.0166 | 1 | Secretory carrier membrane protein 3 |
| SPTBN4 | 0.02181 | 19 | Spectrin, β, nonerythrocytic 4 |
| GDF11 | 0.0245 | 12 | Growth differentiation factor 11 |
| ALDH7A1 | 0.0325 | 5 | Aldehyde dehydrogenase 7 family, member A1 |
| FGD1 | 0.0329 | X | FYVE, RhoGEF, and PH domain containing 1 |
| GRM5 | 0.03411 | 11 | Glutamate receptor, metabotropic 5 |
| CDH2 | 0.03508 | 18 | Cadherin 2, Type 1, N-cadherin (neuronal) |
| JAG1 | 0.03596 | 20 | jagged 1 |
| YIPF2 | 0.03885 | 19 | Yip1 domain family, member 2 |
| CLK2 | 0.04226 | 1 | CDC-like kinase 2 |
| CECR6 | 0.04271 | 22 | Cat eye syndrome chromosome region, candidate 6 |
| ALDH7A1 | 0.04369 | 5 | Aldehyde dehydrogenase 7 family, member A1 |
| BCL11A | 0.04376 | 2 | B-cell CLL/lymphoma 11A (zinc finger protein) |
| KL | 0.04877 | 13 | klotho |
aThe 22 genes (gene symbol or gene name) with AT-associated methylation marks that are significantly (p value) correlated with gene expression.
*p value based on MExGE correlation.