Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CYP450 metabolism regulates swelling-mediated [Ca2+]i responses in Müller glia but not RGCs. A, 140 mOsm HTS induced [Ca2+]i elevations in both cell types; however, only HTS-evoked responses in Müller glia were suppressed by 17-ODYA. B, Normalized cell area measurements in 190 mOsm saline. The CYP450 antagonist suppresses HTS-induced swelling in Müller glia but not in RGCs. NS, Not significant (p > 0.05). **p < 0.01. ****p < 0.0001.
