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. 2014 Nov 12;2:156. doi: 10.1186/s40478-014-0156-0

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© Boza-Serrano et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Increased cytokine levels in BV2 microglia culture medium after α-synuclein activation. Cytokine levels in BV2 microglia culture medium after 12 h incubation with α-synuclein aggregates at concentrations of 5, 10 and 20 μM. α-synuclein aggregates induced a significant increase in cytokine levels of the proinflammatory cytokines TNF-α (A), IL-12 (B) and IL-2 (C). One-way ANOVA, *P < 0.05, **P < 0.01, n = 3, mean ± S.E.M.