Table 2.
Clinical characteristics of patients with juvenile idiopathic arthritis by sex a
| Men with JIA ( n =12) | Women with JIA ( n =19) | P -value | |
|---|---|---|---|
| Age (yr) | 21 | 26 | 0.079 |
| (19.75 to 26.5) | (20.5 to 32.8) | ||
| Height (cm) | 178.8 ± 7.6 | 165.2 ± 7.0 | <0.001 |
| Weight (kg) | 73.3 ± 11.7 | 64.6 ± 12.1 | 0.059 |
| BMI (kg/m2) | 22.9 ± 2.9 | 23.7 ± 4.5 | 0.559 |
| Disease duration (yr) | 11.0 ± 8.2 | 16.9 ± 9.4 | 0.087 |
| Vertebral fractures (n) | 3 | 2 | |
| Nonvertebral fractures (n) | 2 | 4 | |
| Smoking (n) | 3 | 4 | |
| Glucocorticoids (n) | 3 | 9 | 0.230 |
| Menarche (yr) | 13.1 ± 1.2 | ||
| Contraception (n) | 11 | ||
| hsCRP (mg/L) | 9.65 | 13.78 | 0.395 |
| (5.84 to 44.78) | (6.78 to 24.21) | ||
| DAS28 | 6.07 | 6.44 | 0.041 |
| (5.63 to 6.52) | (6.15 to 7.04) | ||
| ESR (mm/hr) | 24.5 | 26.0 | 0.670 |
| (17.0 to 54.0) | (24.0 to 34.5) | ||
| Swollen joints (n) | 11.0 | 12.0 | 0.263 |
| (7.5 to 13.5) | (9.0 to 18.3) | ||
| Tender joints (n) | 13.5 | 17.0 | 0.038 |
| (10.0 to 15.0) | (12.3 to 21.5) | ||
| PGH (mm) | 67.5 | 69.0 | 0.947 |
| (60.0 to 74.5) | (53.8 to 77.5) | ||
| Osteocalcin (μg/L) | 24.3 | 14.3 | 0.016 |
| (20.2 to 28.0) | (11.3 to 23.0) | ||
| PINP (μg/L) | 57.6 | 40.1 | 0.003 |
| (46.3 to 85.6) | (19.9 to 46.4) | ||
| βCTX-I (μg/L) | 0.54 | 0.23 | <0.001 |
| (0.43 to 0.87) | (0.14 to 0.36) | ||
| PTH (pmol/L) | 4.08 | 4.80 | <0.001 |
| (1.73 to 6.05) | (2.50 to 6.15) | ||
| Lumbar spine BMD (g/cm2) | 1.018 | 1.075 | 0.392 |
| (0.913 to 1.201) | (1.012 to 1.221) | ||
| Total femur BMD (g/cm2) | 0.938 | 0.877 | 0.073 |
| (0.887 to 1.131) | (0.764 to 0.916) | ||
| Femoral neck BMD (g/cm2) | 0.934 | 0.875 | 0.092 |
| (0.853 to 1.132) | (0.805 to 0.948) | ||
| Distal radius BMD (g/cm2) | 0.751 | 0.667 | 0.030 |
| (0.677 to 0.792) | (0.606 to 0.704) |
aDisplayed are numbers or means ± SD and/or medians and 75% CIs. BMD: Bone mineral density; BMI: Body mass index; βCTX-I: C-terminal telopeptide of collagen type I; DAS28: Disease Activity Score in 28 joints; ESR: Erythrocyte sedimentation rate; hsCRP: High-sensitivity C-reactive protein; JIA: Juvenile idiopathic arthritis; 25(OH)D: 25-hydroxyvitamin D3; PINP: Procollagen type I N-terminal propeptide; PTH: Parathyroid hormone; PGH: patient global health.