Table 3.
Meta-analysis of the miR-146a rs2910164 polymorphisms and HCC risk
| Genetic model |
Test of association |
Test of heterogeneity |
Publication bias (P value) | ||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | Model | I 2 | P value | ||
| G v C |
1.153 |
1.083-1.228 |
<0.001 |
F |
39.9% |
0.091 |
0.816 |
| GC v CC |
1.165 |
1.054-1.286 |
0.003 |
F |
0.0% |
0.690 |
0.874 |
| GG v CC |
1.361 |
1.192-1.553 |
<0.001 |
F |
43.2% |
0.070 |
0.990 |
| GG/GC v CC |
1.213 |
1.104-1.333 |
<0.001 |
F |
6.7% |
0.380 |
0.927 |
| GG v GC/CC | 1.210 | 1.080 -1.356 | 0.001 | F | 46.1% | 0.054 | 0.846 |
(F: Fixed-effects model).