Table 2.
Association between individual MetS component and coronary parameters according to diabetes status
|
Characteristic |
n |
Any plaque |
Obstructive plaque |
CACS >100 |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||
| No diabetes |
2308 |
|
|
|
| Obesity |
|
|
|
|
| No |
1383 |
1.00 |
1.00 |
1.00 |
| Yes |
925 |
1.27 (1.05–1.55) ‡ |
1.20 (0.91–1.59) |
1.19 (0.88–1.62) |
| Increased blood pressure |
|
|
|
|
| No |
664 |
1.00 |
1.00 |
1.00 |
| Yes |
1644 |
1.25 (1.01–1.55)‡ |
1.59 (1.14–2.23)† |
1.27 (0.89–1.81) |
| Increased triglycerides |
|
|
|
|
| No |
1522 |
1.00 |
1.00 |
1.00 |
| Yes |
786 |
1.37 (1.12–1.68)† |
1.56 (1.18–2.06)† |
1.18 (0.87–1.62) |
| Decreased HDL |
|
|
|
|
| No |
1616 |
1.00 |
1.00 |
1.00 |
| Yes |
692 |
1.35 (1.09–1.68)† |
1.55 (1.14–2.10)† |
1.57 (1.12–2.19)† |
| Increased fasting glucose |
|
|
|
|
| No |
1640 |
1.00 |
1.00 |
1.00 |
| Yes |
668 |
1.22 (0.99–1.50) |
0.97 (0.72–1.31) |
1.24 (0.90–1.69) |
| Type 2 diabetes |
561 |
|
|
|
| Obesity |
|
|
|
|
| No |
288 |
1.00 |
1.00 |
1.00 |
| Yes |
273 |
1.27 (0.85–1.90) |
0.86 (0.57–1.31) |
1.12 (0.72–1.75) |
| Increased blood pressure |
|
|
|
|
| No |
140 |
1.00 |
1.00 |
1.00 |
| Yes |
421 |
1.03 (0.65–1.63) |
0.76 (0.48–1.21) |
1.11 (0.66–1.86) |
| Increased triglycerides |
|
|
|
|
| No |
315 |
1.00 |
1.00 |
1.00 |
| Yes |
246 |
1.34 (0.89–2.02) |
1.00 (0.65–1.53) |
0.93 (0.59–1.47) |
| Decreased HDL |
|
|
|
|
| No |
347 |
1.00 |
1.00 |
1.00 |
| Yes | 214 | 0.92 (0.60–1.40) | 1.44 (0.93–2.24) | 1.13 (0.70–1.82) |
All models are adjusted for age, sex, current smoking, LDL, and GFR. CACS, coronary artery calcium score; CI, confidence intervals; GFR, glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein, MetS, metabolic syndrome; OR, odds ratios. *P <0.001; †P <0.01; ‡P <0.05.