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Relative frequency of rare variants (rare variants for Kb of coding sequence) in late-onset AD (LOAD) cases and controls (CTRLS) in APP, PSEN1, PSEN2, MAPT, GRN, PRNP
| Gene | LOAD cases (n = 141) | CTRLS (n = 179) |
|---|---|---|
| APP | 0.4/Kb | 1.2/Kb |
| PSEN1 | 0.6/Kb | 0/Kb |
| PSEN2 | 3.7/Kb | 1.5/Kb |
| MAPT | 1.3/Kb | 0.8/Kb |
| GRN | 1.1/Kb | 1.1/Kb |
| PRNP | 0/Kb | 1.3/Kb |
