Table 2.
Most common treatment-related adverse events
| Adverse eventa | All grades | Grade 3/4 |
|---|---|---|
| n (%) | n (%) | |
| Any treatment-related AE | 56 (93) | 21 (35) |
| Diarrhea | 38 (63) | 4 (7) |
| Fatigue | 33 (55) | 3 (5) |
| Nausea | 27 (45) | 1 (2) |
| Hypertension | 25 (42) | 8 (13) |
| Weight decrease | 19 (32) | 4 (7) |
| Anorexia | 18 (30) | 0 |
| Stomatitis | 18 (30) | 0 |
| Dyspepsia | 17 (28) | 0 |
| Headache | 17 (28) | 2 (3) |
| Mucosal inflammation | 15 (25) | 0 |
| Proteinuria | 15 (25) | 5 (8) |
| Palmar-plantar erythrodysesthesia syndrome | 13 (22) | 1 (2) |
| Rash | 13 (22) | 0 |
| Dysgeusia | 12 (20) | 0 |
| Hoarseness | 12 (20) | 0 |
AE adverse event
aReported in ≥20 % of patients