Table 3.
Kidney tissue | Treatment | 1 h | 24 h | 48 h | 72 h |
---|---|---|---|---|---|
Cortex |
CG |
19.0 ± 2.3 |
18.9 ± 2.1 |
19.2 ± 2.2 |
18.9 ± 2.7 |
|
DN PC |
24.5 ± 3.6* |
24.5 ± 4.3* |
24.7 ± 4.5* |
25.4 ± 3.7* |
|
DN 200 |
31.1 ± 3.2* |
31.3 ± 4.9* |
30.9 ± 3.6* |
28.9 ± 4.3* |
|
DN 240 |
33.3 ± 4.6* |
34.8 ± 4.8* |
34.0 ± 3.1* |
33.5 ± 7.9* |
|
DN 300 |
41.7 ± 5.1* |
41.9 ± 3.4* |
40.1 ± 5.5* |
39.2 ± 4.0* |
|
DN 350 |
46.7 ± 5.2* |
50.2 ± 5.8* |
48.9 ± 5.7* |
43.7 ± 6.0* |
|
DN 400 |
50.1 ± 5.6* |
57.6 ± 5.3* |
53.9 ± 6.1* |
47.4 ± 5.5* |
Outer medulla |
CG |
20 ± 4.2 |
22.7 ± 4.8 |
22.4 ± 5.4 |
21.6 ± 5.1 |
|
DN PC |
29.9 ± 4.4* |
30.7 ± 5.1* |
28.2 ± 5.8* |
29.5 ± 5.4* |
|
DN 200 |
38.1 ± 4.6* |
40.1 ± 6.2* |
37.5 ± 4.8* |
33.8 ± 5.8* |
|
DN 240 |
42.3 ± 3.5* |
43.3 ± 5.7* |
40.3 ± 4.2* |
37.3 ± 3.5* |
|
DN 300 |
53.4 ± 5.2* |
57.9 ± 5.6* |
48.8 ± 4.8* |
45.4 ± 5.2* |
|
DN 350 |
60.6 ± 6.3* |
72.4 ± 5.7* |
62.9 ± 5.5* |
56.5 ± 5.3* |
|
DN 400 |
67.6 ± 5.6* |
80.4 ± 6.3* |
74.7 ± 6.1* |
67.7 ± 5.8* |
Inner medulla |
CG |
20.2 ± 2.4 |
20.0 ± 3.6 |
21.8 ± 2.7 |
20.5 ± 3.2 |
|
DN PC |
22.7 ± 4.7* |
24.5 ± 3.8* |
24.3 ± 4.0* |
22.9 ± 3.4* |
|
DN 200 |
27.2 ± 3.3* |
30.6 ± 4.0* |
26.2 ± 2.7* |
25.0 ± 3.5* |
|
DN 240 |
30.4 ± 3.8* |
33.6 ± 5.8* |
31.9 ± 4.2* |
29.9 ± 5.2* |
|
DN 300 |
42.8 ± 5.2* |
44.2 ± 5.0* |
38.8 ± 4.9* |
32.7 ± 4.8* |
|
DN 350 |
49.2 ± 5.7* |
50.2 ± 4.8* |
47.3 ± 5.8* |
39.4 ± 5.1* |
DN 400 | 55.2 ± 5.4* | 57.2 ± 5.3* | 55.3 ± 6.3* | 46.4 ± 5.7* |
Abbreviations:CG control group, DN diabetic nephropathy, PC positive control; 200 200 mg I/mL contrast agent; 240 240 mg I/mL contrast agent, 300 300 mgI/mL contrast agent, 350 350 mg I/mL contrast agent, 400 400 mg I/mL contrast agent.
The control group and the DN PC group were injected with physiological saline/.
Values are means ± standard deviation.
*P < 0.05 vs. the control group.