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. 2014 Sep 2;14:145. doi: 10.1186/1471-2466-14-145

Table 3.

Association between quintiles of TSH and parameters of spirometry and cardiopulmonary exercise testing

  First quintile #
Second quintile #
Fourth quintile #
Fifth quintile #
(0 – 0.5745 mIU/L)
(0.5745 – 0.839 mIU/L)
(1.14 – 1.59 mIU/L)
(1.59 – 10.00 mIU/L)
β (95%-CI) β (95%-CI) β (95%-CI) β (95%-CI)
FEV 1 ; l
0.00 (-0.06; 0.07)
0.02 (-0.05; 0.08)
-0.01 (-0.07; 0.05)
0.01 (-0.05; 0.07)
FVC; l
-0.01 (-0.08; 0.06)
-0.01 (-0.08; 0.07)
-0.002 (-0.073; 0.069)
0.005 (-0.073; 0.083)
FEV 1 /FVC; %
0.31 (-0.38; 0.99)
-0.02 (-0.75; 0.71)
-0.14 (-0.80; 0.52)
-0.45 (-1.13; 0.24)
peakVO 2 ; ml/min
-32.3 (-73.1; 8.5)
-48.5* (-89.2: -7.9)
-35.3 (-79.8; 9.3)
-16.6 (-60.5; 27.4)
VO 2 @AT; ml/min
2.4 (-21.8; 26.6)
-3.7 (-28.3; 20.9)
-11.1 (-34.5; 12.4)
-8.2 (-30.7; 14.3)
O 2 HR; ml/beat
-0.06 (-0.35; 0.24)
-0.25 (-0.53; 0.02)
-0.28 (-0.56; 0.01)
-0.32* (-0.59; -0.05)
V E vs. VCO 2 slope
-0.20 (0.66; 0.27)
-0.24 (-0.71; 0.23)
0.20 (-0.23; 0.64)
0.04 (-0.40; 0.48)
Maximum power; watt
-3.7* (-7.1; -0.3)
-3.1 (-6.7; 0.5)
-2.7 (-6.0; 0.6)
0.2 (-3.2; 3.5)
Exercise duration; minutes -0.22* (-0.41; -0.03) -0.15 (-0.35; 0.04) -0.18 (-0.39; 0.03) -0.07 (-0.29; 0.15)

Median regression adjusted for age, sex, height, weight, beta blocker intake, smoking status, physical activity, and time between examinations.

*p < 0.05.

#Reference: Third quintile 0.839 – 1.14 mIU/L.