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Effect of delaying initiation of GCV and CDV treatment regimens. Mice were infected with virus (HVP2 OU1-76, dark gray; HVP2 X313, light gray; BV, black) and treated with the minimal 100% protective dose of GCV (100 mg/kg daily) or CDV (25 mg/kg daily). Mice received a 7-d treatment regimen, with groups starting treatment on the indicated day after infection (samples were not collected on days –1 and 0) from HVP2 X313-infected mice treated with GCV.
