. Author manuscript; available in PMC: 2014 Nov 19.

Published in final edited form as: Nature. 2014 Jan 22;506(7487):179–184. doi: 10.1038/nature12929

Extended Data Table 6a. Mammalian conservation at de novo mutation sites and of genes hit by de novo SNVs.

Mann-Whitney rank test of the Genomic Evolutionary Rate Profiling (GERP) score (see Supplementary Text) distributions of nonsynonymous (NS) de novo mutations between pairs of phenotypes, with significant pairwise comparisons (p<0.05) in bold.

		ID^10,11	ASD^6-9	Current study
	median (N)	4.89 (141)	4.72 (780)	4.48 (481)
ID^10,11	4.89 (141)	-	0.028	0.00053
ASD^6-9	4.72 (780)	0.972	-	0.013
Current study	4.48 (481)	0.999	0.987	-