Table 4.
DTI scalars of different WM ROIs for NBOs, NASs and controls (mean value ± SD).
| ROI | n | Group | FA |
ADC (×10−3mm2/s) |
λ1 (×10−3mm2/s) |
λ2 (×10−3mm2/s) |
λ3 (×10−3mm2/s) |
RD (×10−3mm2/s) |
| CP | 7 | NBO | 0.31±0.11 | 1.00±0.10 | 1.27±0.15 | 0.94±0.08 | 0.79±0.11 | 0.86±0.09 |
| NAS | 0.40±0.11 | 0.88±0.09 | 1.21±0.15 | 0.79±0.07 | 0.63±0.11 | 0.71±0.08 | ||
| Control | 0.33±0.08 | 1.13±0.40 | 1.50±0.44 | 1.05±0.40 | 0.83±0.37 | 0.94±0.38 | ||
| Pons | 6 | NBO | 0.31±0.09 | 0.98±0.08 | 1.25±0.16 | 0.95±0.05 | 0.75±0.08 | 0.85±0.05 |
| NAS | 0.34±0.12 | 0.86±0.03 | 1.13±0.05 | 0.83±0.05 | 0.62±0.08 | 0.73±0.03 | ||
| Control | 0.32±0.06 | 0.98±0.20 | 1.31±0.26 | 0.91±0.17 | 0.70±0.19 | 0.81±0.18 | ||
| CC | 5 | NBO | 0.21±0.09 | 1.16±0.11 | 1.66±0.18 | 1.00±0.07 | 0.82±0.11 | 0.91±0.09 |
| NAS | 0.31±0.09 | 0.92±0.05 | 1.58±0.13 | 0.68±0.08 | 0.50±0.10 | 0.59±0.09 | ||
| Control | 0.63±0.06 | 0.92±0.12 | 1.68±0.15 | 0.62±0.13 | 0.46±0.11 | 0.54±0.12 | ||
| PLIC | 3 | NBO | 0.33±0.08 | 0.91±0.10 | 1.37±0.21 | 0.80±0.10 | 0.57±0.15 | 0.68±0.13 |
| NAS | 0.40±0.11 | 0.90±0.10 | 1.30±0.10 | 0.83±0.06 | 0.57±0.15 | 0.70±0.10 | ||
| Control | 0.46±0.11 | 0.81±0.06 | 1.26±0.09 | 0.67±0.10 | 0.49±0.11 | 0.58±0.10 | ||
| MI | 2 | NBO | 0.29±0.10 | 1.03±0.05 | 1.30±0.14 | 1.00±0.00 | 0.80±0.00 | 0.90±0.00 |
| NAS | 0.50±0.21 | 0.95±0.07 | 1.25±0.21 | 0.90±0.00 | 0.70±0.00 | 0.80±0.00 | ||
| Control | 0.40±0.09 | 0.90±0.00 | 1.34±0.12 | 0.76±0.09 | 0.61±0.04 | 0.68±0.06 | ||
| CWM | 1 | NBO | 0.12 | 1.07 | 1.50 | 0.90 | 0.80 | 0.85 |
| NAS | 0.09 | 0.83 | 1.20 | 0.70 | 0.60 | 0.65 | ||
| Control | 0.52 | 0.72 | 1.19 | 0.54 | 0.42 | 0.48 | ||
| FWM | 1 | NBO | 0.36 | 1.27 | 1.50 | 1.20 | 1.10 | 1.15 |
| NAS | 0.45 | 1.10 | 1.40 | 1.10 | 0.80 | 0.95 | ||
| Control | 0.45 | 0.87 | 1.34 | 0.74 | 0.54 | 0.64 | ||
| LB | 1 | NBO | 0.28 | 1.03 | 1.20 | 1.00 | 0.90 | 0.95 |
| NAS | 0.26 | 0.93 | 1.00 | 0.90 | 0.90 | 0.90 | ||
| Control | 0.16 | 2.28 | 2.66 | 2.15 | 2.03 | 2.09 | ||
| Total | 26 | NBO | 0.29±0.10 | 1.03±0.12 | 1.37±0.22 | 0.95±0.10 | 0.78±0.14 | 0.87±0.12 |
| NAS | 0.36±0.13 | 0.90±0.08 | 1.28±0.20 | 0.80±0.11 | 0.62±0.13 | 0.71±0.11 | ||
| Control | 0.41±0.14 | 1.02±0.36 | 1.48±0.38 | 0.88±0.38 | 0.69±0.37 | 0.79±0.38 | ||
|
ADC, apparent diffusion coefficient; CC, corpus callosum; CP, cerebellar peduncles; CWM, cerebellar white matter; FA, fractional anisotropy; DWM, frontal white matter; LB, lower brain stem; MI, midbrain; NAS: normal-appearing site (contralateral to NBO); NBO, neurofibromatosis bright object; PLIC, posterior limb of the internal capsule; RD, radial diffusivity; ROI, region of interest; SD, standard deviation; WM, white matter. | ||||||||