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. 2014 Mar 12;21(7):e39–e47. doi: 10.1111/jvh.12236

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© 2014 The Authors. Journal of Viral Hepatitis published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Analysis of T-lymphocyte proliferation and cytokine production. (a, b) Flow cytometric analysis demonstrating the percentage of decreased fluorescence intensity of PHA-stimulated and non-PHA-stimulated CFSE-labelled T cells from the two groups. The percentage is indicated on the upper left side of the cytometric graph. (a) Healthy control group; (b) patient group. (c) Comparative analysis data of CDI in the two groups. (d) Comparative analysis data of IFN-γ and IL-2 production by T cells harvested from HSC/OP9-DL1 of the two groups following stimulation with PHA for 72 h. The data are represented as mean values ± SD of individual experiments. P-values were determined using Student's t test (*P < 0.05).