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Plasma glucose (A) and insulin (B) excursions in diabetic Zucker fatty diabetic (ZDF) rats infused intravenously with 100 pmol/kg/min AC163794 and glucose-dependent insulinotropic peptide (GIP) during an intravenous glucose tolerance test (IVGTT). Insets represent calculated AUC for glucose (A) and insulin (B) excursion curves. Data are presented as mean ± SEM. *p < 0.05 versus vehicle control (n = 5–7 per group).
