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Adoptive transfer of M2 macrophages at day 15 postimmunization (p.i) diminishes the severity of established EAE. M2 macrophages were injected intravenously into MOG-EAE DBA/1 mice at two time points p.i: (A) day 0 and (B) day 15. Comparison of accumulative clinical scores between PBS-treated EAE mice and M2 macrophage-treated EAE mice is presented for each time point. *P < 0.05. Data represent two independent experiments.
