Table 2.
Comparison of the numbers of cysts in lung specimens from patients with Birt–Hogg–Dubé syndrome (BHDS) and primary spontaneous pneumothorax (PSP) [no. (%)]
| Histological findings | Cysts from BHDS patients (n = 229) | Cysts from PSP patients (n = 117) | χ2 -test |
|---|---|---|---|
| Cysts located in | |||
| Subpleural area | 116 (50.7) | 115 (98.3) | P < 0.001 |
| Intrapulmonary area | 113 (49.3) | 2 (1.7) | |
| Cysts abutting on | |||
| Interlobular septa | 202 (88.2) | 16 (13.7) | P < 0.001 |
| Bronchiole | 11 (4.8) | 42 (35.9) | P < 0.001 |
| Intracystic septa | 31 (13.6) | 0 (0) | P < 0.001 |
| Venules protruding into the cyst | 90 (39.5) | 2 (1.7) | P < 0.001 |
| Cysts without inflammation | |||
| Total | 125/229 (54.6) | 2/117 (1.7) | P < 0.001 |
| Subpleural area | 37/116 (31.9) | 2/115 (1.7) | P < 0.001 |
| Intrapulmonary area | 88/113 (77.9)* | 0/2 (0) | NS (P = 0.177) |
*
P < 0.001 for comparison of the numbers of cysts without inflammation between the subpleural and intrapulmonary areas.
NS, not significant.