Table 2.
Total atherosclerotic score (TAS) for the whole body and AS for separate arterial territories and their correlation with CIMT and ΔCIMT over 5 years
| TAS/AS vs. IMT and ΔIMT | ||||||
|---|---|---|---|---|---|---|
| Adjusted for sex | Adjusted for multiple factors | |||||
| Beta | 95% CI | P-value | Beta | 95% CI | P-value | |
| CIMT | ||||||
| Whole body (TAS) | 0·61 | 0·317 to 0·903 | 0·0001 | 0·358 | 0·053 to 0·663 | 0·0221 |
| Carotids (AS) | 0·19 | −0·03 to 0·42 | 0·098 | 0·14 | −0·08 to 0·37 | 0·22 |
| Aorta (AS) | 0·36 | 0·08 to 0·64 | 0·013 | 0·28 | −0·1 to 0·56 | 0·058 |
| Renals (AS) | 0·37 | −0·31 to 1·06 | 0·288 | 0·2 | −0·49 to 0·89 | 0·567 |
| Upper legs (AS) | 0·21 | 0·04 to 0·38 | 0·17 | 0·18 | 0·01 to 0·36 | 0·42 |
| Lower legs (AS) | 0·31 | 0·1 to 0·52 | 0·004 | 0·25 | 0·04 to 0·47 | 0·019 |
| ΔCIMT | ||||||
| Whole body (TAS) | −0·342 | −0·765 to 0·081 | 0·1144 | −0·168 | −0·566 to 0·231 | 0·41 |
| Carotids (AS) | −0·14 | −0·48 to 0·2 | 0·423 | −0·18 | −0·51 to 0·15 | 0·297 |
| Aorta (AS) | 0·01 | −0·04 to 0·43 | 0·949 | 0·08 | −0·33 to 0·49 | 0·703 |
| Renals (AS) | 0·16 | −0·79 to 1·11 | 0·74 | 0·06 | −0·86 to 0·98 | 0·894 |
| Upper legs (AS) | −0·23 | −0·49 to 0·03 | 0·86 | −0·18 | −0·44 to 0·08 | 0·175 |
| Lower legs (AS) | −0·31 | −0·63 to 0 | 0·51 | −0·24 | −0·55 to 0·07 | 0·13 |
CIMT was significantly correlated with TAS when adjusted for sex as well as multiple factors. When divided into the five territories, CIMT was only significantly correlated with AS in the aorta (adjusted for sex) and in the lower legs (adjusted for both sex and multiple factors). ΔCIMT over 5 years did not correlate significantly with TAS.
TAS, total atherosclerotic score; AS, atherosclerotic score; CIMT, carotid intima–media thickness; ΔCIMT, change in CIMT over 5 years (from age 70–75), multiple factors, antihypertensive medication at age 70 and 75; systolic blood pressure at age 70 and 75; statins at age 70 and 75; and LDL cholesterol at age 70 and 75.