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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Autoimmunity. 2014 May 6;47(6):409–418. doi: 10.3109/08916934.2014.914507

Figure 3. MTX inhibits arthritis in IDO ko mice.

Figure 3

(A) KRN B6.g7 (IDO wt) and (B) KRN IDO ko B6.g7 (IDO ko) mice were treated with MTX (1mg/kg) or carrier alone starting at the age of 3wk and followed for the development of arthritis. The graphs show mean ankle thickness ± SEM for n=9 IDO wt and n=6 IDO ko mice per treatment group pooled from two independent experiments. *p<0.05, n.s., not significant.