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. 2014 Oct 23;5(10):e1483. doi: 10.1038/cddis.2014.385

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Copyright © 2014 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International Licence. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons licence, users will need to obtain permission from the licence holder to reproduce the material. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0

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Sirtuin 1 is overexpressed in primary synovial sarcoma tumors compared with normal mesenchymal cells. (a) Quantitative expression of SIRT1 and SIRT2 was determined by QRT-PCR in RNA samples obtained from fresh frozen synovial sarcomas, synovial sarcoma cell lines (1273-99, Syo1, Bax) rhabdomyosarcoma cell lines (RD, RMS and RH30), a malignant peripheral nerve sheath tumor (MPNST) cell line (740728), in three different primary mesenchymal stem cells: MSC 1–3 and in human diploid fibroblasts hF. Relative expression denotes ΔCT values of SIRT1 or SIRT2 in relation to GAPDH. (b) Graphic presentation of SIRT1 and SIRT2 expression in grouped samples. Student's t-test showed no statistical difference among the groups (NS)