Table 2. In vivo anti cancer activity of BA and HBA.
|
Average body weights(g) of animals on days |
Day 13 |
||||||
|---|---|---|---|---|---|---|---|
| Treatment groups | 1 | 5 | 9 | Av. body weights (g) | Av. tumor weights (mg) | % Tumor growth inhibition | Mortality |
| BA (50 mg/kg i.p.) | 20.14 | 21.71 | 21.81 | 22.57 | 1215.78±51.8** | 28.05 | 0/7 |
| BA (100 mg/kg i.p.) | 20.28 | 21.28 | 22.00 | 22.28 | 1031.5±54.21*** | 39.00 | 0/7 |
| HBA (40 mg/kg i.p.) | 20.42 | 21.42 | 21.85 | 22.70 | 1116±96.78*** | 33.96 | 0/7 |
| 5-Florouracil-positive control (22 mg/kg i.p.) | 20/71 | 21.42 | 20.71 | 20.85 | 817.5±33.71*** | 52.05 | 0/7 |
| Normal saline NS (0.2 ml i.p.) | 20.80 | 21.50 | 22.80 | 23.50 | 1689.95±88.68 | — | 0/10 |
Values are mean±S.E. (n=7, 10 for control). *P<0.05, **P<0.01, ***P<0.001 versus normal saline control