Figure 2.

SA3N accelerated diabetic wound closure. (a) Representative digital images of non-diabetic and diabetic mice wounds captured over 35 days wound-healing period. (b) Comparison of the percentages of the open wound size over 35 days healing period between vehicle- (n=17) and SA3N-treated diabetic mice (n=14), showing that SA3N-treated wounds healed significantly faster than vehicle-treated wounds and that the healing rate was similar to that of non-diabetic wounds. (Open circles represent replicates of saline-treated wounds and closed circles represent replicates of SA3N-treated wounds. P-values were calculated using unpaired Student t-test. *P<0.05, ***P<0.001, ****P<0.0001 between vehicle and SA3N-treated wounds.)