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. 2014 Oct 23;5(10):e1479. doi: 10.1038/cddis.2014.430

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Copyright © 2014 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International Licence. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons licence, users will need to obtain permission from the licence holder to reproduce the material. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0

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Mir-30d promotes cardiomyocyte pyroptosis. (a) Concentrations of IL-1β and IL-18 in the serum and mRNA levels in the hearts of the control, mir-30d and NC groups. (b) Concentrations of IL-1β and IL-18 in the serum and mRNA levels in the HG, HG+AMO-mir-30d and HG+AMO-NC groups. (c) TUNEL (terminal deoxinucleotidyl transferase-mediated dUTP-fluorescein nick end labeling) images showing cell death in the control, HG, HG+ mir-30d and HG+AMO-mir-30d groups. Blue, nuclear staining (DAPI); green, TUNEL staining; TUNEL nuclear localization in merged image. Scale bar: 20 μm. n=3. *P<0.05 and **P<0.01 versus control; ^#P<0.05 and ^##P<0.01 versus mir-30d; ⁺P<0.05 and ⁺⁺P<0.01 versus HG; ^§P<0.05 versus HG+AMO-mir-30d; mean±S.E.M.