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. 2014 Nov 19;9(11):e112749. doi: 10.1371/journal.pone.0112749

Figure 4. Effect of HI on the neutralization capacity of pre- and post-immune sera from AGM experimentally infected with PR8.

Figure 4

Two AGMs were inoculated with PR8 as described in the Materials and Methods. Pre-immune sera (d 0) and sera collected at d 14 post-infection were tested at the indicated fold dilutions for in vitro neutralization of PR8-GFP as described in Fig. 2. Results are expressed as the mean plus SD from triplicate experiments to determine the percentage of GFP-positive cells compared to in vitro control infections (which lacked serum treatment). *** p<0.0001 as compared to matching serum treatment for the same animal at day 0 (shown on day 14 values) based on t-tests on log transformed neutralization percentages.