Table 3. Risk factors for atazanavir-associated urolithiasis, univariate analysis.

	OR	95% CI	p
Male sex	2.1	0.66–6.69	0.21
BMI (kg/m2)	0.93	0.84–1.04	0.24
Age (years)	1	0.95–1.04	0.83
Plasma HIV RNA <50 cp/mL	0.07	0–0.44	<0.01
RNA <50 cp/mL
Previous history of urolithiasis	6.86	2.35–20.03	<0.001
Prior treatment with indinavir	3.25	1.33–7.96	<0.01
Duration of atazanavir (per year)	1.37	1.04–1.79	<0.03
Ritonavir (100 mg od)	9.38	1.21–72.9	<0.04
Associated antiretroviral therapy	0.8	0.34–1.85	0.60
Creatinine clearance (baseline)	0.99	0.97–1.01	0.39
Serum free bilirubin level (per 2-fold increase)	2.08	1.19–3.62	<0.01
Any chronic liver disease	2.56	0.81–8.11	0.11
Chronic hepatitis B	1.00	0.10–9.99	1
Chronic hepatitis C	6.77	1.17–39.07	<0.04