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. 2014 Nov 19;9(11):e112722. doi: 10.1371/journal.pone.0112722

Table 6. 26 pathways were related to immune and diseases in all pathways.

KEGG Pathway Pathway Hierarchy 2 Target gene of different expression miRNA
Toll-like receptor signaling pathway Immune system JNK, TLR5, TBK1
Hepatitis C Infectious diseases: Viral JNK, TBK1, LDLR
Salmonella infection Infectious diseases: Bacterial JNK, TLR5
Fc epsilon RI signaling pathway Immune system JNK, FYN
Tuberculosis Infectious diseases: Bacterial JNK, PLK3, CTSS
Influenza A Infectious diseases: Viral JNK, DNAJB1, TBK1
Measles Infectious diseases: Viral FYN, TBK1
MAPK signaling pathway Signal transduction JNK, MKP
Toxoplasmosis Infectious diseases: Parasitic JNK, LDLR
Chemokine signaling pathway Immune system CCR7, ADCY7, DOCK2
HTLV-I infection Infectious diseases: Viral JNK, ADCY7, SLC2A1
Herpes simplex infection Infectious diseases: Viral JNK, TBK1
Fc gamma R-mediated phagocytosis Immune system DOCK2
Prion diseases Neurodegenerative diseases FYN
Viral myocarditis Cardiovascular diseases FYN
Pathways in cancer Cancers: Overview JNK, SLC2A1
Transcriptional misregulation in cancer Cancers: Overview CCR7
Type II diabetes mellitus Endocrine and metabolic diseases JNK
Cytokine-cytokine receptor interaction Signaling molecules and interaction CCR7, TNFSF12
Antigen processing and presentation Immune system CTSS
Pertussis Infectious diseases: Bacterial JNK
Natural killer cell mediated cytotoxicity Immune system FYN
T cell receptor signaling pathway Immune system FYN
Chagas disease Infectious diseases: Parasitic JNK
Staphylococcus aureus infection Infectious diseases: Bacterial CFB
Complement and coagulation cascades Immune system CFB

List of gene abbreviations: JNK: c-Jun N-terminal kinase, TLR5: toll-like receptor 5, TBK1: TANK-binding kinase 1, LDLR: low-density lipoprotein receptor, FYN: tyrosine-protein kinase Fyn, CTSS: cathepsin S, PLK3: polo-like kinase 3, DNAJB1: DnaJ homolog subfamily B member 1, MKP: dual specificity MAP kinase phosphatase, DOCK2: dedicator of cytokinesis protein 2, ADCY7: adenylate cyclase 7, SLC2A1: MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1, CCR7: C-C chemokine receptor type 7, TNFSF12: tumor necrosis factor ligand superfamily member 12, CFB: component factor B.