Figure 5. Rapamycin attenuated the inflammatory cell infiltration after LAD ligation.

The representative images and statistical result of immunohistochemical assay of the infarct border zone of different time points after LAD ligation to test the infiltration of CD45⁺ leukocytes, including CD68⁺ macrophages (n = 5, *P<0.05 vs Sham; #P<0.05 vs CTL). Sham, mice without LAD ligation; CTL, LAD ligation with saline; Rapa, LAD ligation with Rapamycin treatment; 3MA, LAD ligation with 3MA treatment.