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. 2014 Nov 19;9(11):e112518. doi: 10.1371/journal.pone.0112518

Table 3. MIC of antifungals alone and with increasing concentrations of OligoG (2, 6, 10%) for a range of Candida spp.

MIC (mg/L) at indicated OligoG concn (%)
Nystatin Fluconazole* Terbinafine
Isolate 0 2 6 10 0 2 6 10 0 2 6 10
C. albicans CCUG 39343 8 8 4 2 16 16 8 4 >32 >32 >32 >32
C. parapsilosis ATCC 22019T 8 4 1 0.5 2 2 0.5 0.25 2 2 2 2
C. krusei 141/03 8 4 2 2 128 64 64 64 >32 >32 >32 >32
C. krusei 249/03(2) 8 8 8 4 8 4 2 1 4 4 8 4
C. lusitaniae 994/01(2) 8 8 2 1 0.5 0.25 <0.13 <0.13 8 4 4 2
C. tropicalis 12 8 8 4 4 1 1 <0.13 <0.13 >32 16 >32 32
C. tropicalis 519468 16 8 4 2 1 1 0.25 <0.13 >32 >32 >32 >32
C. tropicalis 250/03 8 4 2 1 8 4 2 2 >32 >32 >32 >32
C. tropicalis T2.2 8 8 4 2 0.5 0.25 <0.13 <0.13 >32 >32 >32 32

*MIC values of fluconazole for C. tropicalis strains (519468 and T2.2) were determined at 36 h.

Bold numbers indicate a Fractional Inhibitory Concentration Index (FICI)≤0.5; indicative of synergy [25].