Table 4. Phenotypic Characteristics of Bacteriophage φ6 Mutants.
Strain | Mutation | Frequency of Mutant | Fitness ERA | Fitness PP | Plaque Size ERAa | Attachment rate to ERAb | Attachment rate to PP |
S8 | D554G | 2 | 3.31 | 14.73 | 6.89 | 2.58×10−11 | 4.79×10−11 |
S68 | E8D | 4 | 1.97 | 14.61 | 5.69 | 2.22×10−11 | 4.72×10−11 |
S53 | E8A | 4 | 3.97 | 14.57 | 7.8 | 4.80×10−11 | 4.68×10−11 |
S46 | Q130R/S299W | 1 | 0.98 | 14.80 | 9.26 | 1.68×10−11 | 5.05×10−11 |
S42 | S161P/L555F | 1 | 2.20 | 14.93 | 9.17 | 2.40×10−11 | 5.31×10−11 |
S4 | Q130R | 1 | 1.27 | 14.74 | 6.28 | 2.05×10−11 | 5.41×10−11 |
S30 | E8K/Q130R | 1 | 2.51 | 14.62 | 3.54 | 2.49×10−11 | 5.71×10−11 |
S28 | E8A/F46L | 1 | 2.47 | 15.21 | 5.94 | 2.53×10−11 | 5.63×10−11 |
S26 | D554A | 1 | 4.47 | 14.77 | 7.85 | 2.39×10−11 | 5.63×10−11 |
S154 | E8G | 24 | 4.12 | 14.92 | 6.29 | 2.59×10−11 | 5.33×10−11 |
S14 | E8K/D554G | 1 | 2.08 | 14.79 | 6.56 | 2.09×10−11 | 4.50×10−11 |
S13 | E8K/F46S | 1 | 3.16 | 14.85 | 10.25 | 2.24×10−11 | 4.60×10−11 |
S117 | E8K | 20 | 3.91 | 14.66 | 8.93 | 2.51×10−11 | 4.39×10−11 |
φ6 WT | n/a | n/a | n/a | 15.07 | n/a | n/a | 4.91×10−11 |
= in mm2; b = Attachment rate (k) units are per milliliter per cell (or per phage) per minute.