Table 4. Multivariate analysis of the determinants of capsaicin cough hypersensitivity.
Variables | C5≤62.5 µmol (No., %) | C5>62.5 µmol (No., %) | Multivariable regression model | ||
OR | 95%CI | P | |||
Sex | |||||
Male | 11 (21.2) | 41 (49.4%) | - | Reference | - |
Female | 41 (78.8%) | 42 (50.6%) | 3.25 | 1.35-7.83 | <0.01 |
HRCT total score | |||||
≤6 | 16 (30.8%) | 50 (60.2%) | - | Reference | - |
7-12 | 28 (53.8%) | 26 (31.3%) | 2.57 | 1.07-6.17 | 0.04 |
≥13 | 8 (15.4%) | 7 (8.4%) | 2.32 | 0.66-8.17 | 0.19 |
BSI | |||||
0-4 | 11 (21.2%) | 41 (49.4%) | - | Reference | - |
5-8 | 24 (46.2%) | 25 (30.1%) | 4.05 | 1.48-11.06 | <0.01 |
≥9 | 17 (32.7%) | 17 (20.5%) | 4.38 | 1.48-12.93 | <0.01 |
Categorical data were expressed as number (percentage) and compared with chi-square test.
Data in boldface indicated statistical significance.
In multivariate analysis, settings of the covariates were as follows: Sex: 0 for female, 1 for males; duration of cough: 0 for less than 5 years, 1 for 5 to 10 years, 2 for greater than 10 years; HRCT score: 0 for 6 or less, 1 for greater than 7 and less than 13, 2 for 13 or greater; bronchiectasis severity index: 0 for 4 or less, 1 for 5 to 8, 2 for 9 or greater; 24-hour sputum volume: 0 for 10 ml or less, 1 for greater than 10 and less than 30 ml, 2 for 30 ml or greater; cough symptom score: 0 for 5 or less, 1 for greater than 5; sputum bacteriology: 0 for commensals, 1 for Pseudomonas aeruginosa, 2 for other PPMs.