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. 2014 Nov 19;9(11):e113294. doi: 10.1371/journal.pone.0113294

Table 7. The LB-vaccine is highly efficacious when administered at a nanogram dose.

Treatment Infected/Total
Immunogen Dose Exp. 1 Exp. 2
LB-vaccine 1.5 µg 1/7** 0/9**
0.15 µg 0/6** 0/10**
0.015 µg 1/7** 1/9*
Placebo 7/7 7/9

Immunized mice were challenged with B. afzelii infected ticks, in two separate experiments and only data from mice where at least one fully fed tick was collected are presented. The p-values were calculated with Fisher’s exact test (two tailed); * p<0.05 and ** p<0.01.