Table 7. The LB-vaccine is highly efficacious when administered at a nanogram dose.
Treatment | Infected/Total | ||
Immunogen | Dose | Exp. 1 | Exp. 2 |
LB-vaccine | 1.5 µg | 1/7** | 0/9** |
0.15 µg | 0/6** | 0/10** | |
0.015 µg | 1/7** | 1/9* | |
Placebo | – | 7/7 | 7/9 |
Immunized mice were challenged with B. afzelii infected ticks, in two separate experiments and only data from mice where at least one fully fed tick was collected are presented. The p-values were calculated with Fisher’s exact test (two tailed); * p<0.05 and ** p<0.01.