Table 4. Meta-analysis of cylin D1(CCND1) polymorphism and risk of NPC.
Genetic comparison | Begger’s test(z, p) | Egger’s test(t, p) | OR(95%CI) | POR | I2 (%) | Effect model |
Overall (6) | ||||||
A vs. G | 0.00, 1.000 | −0.26, 0.807 | 0.84(0.62,1.15) | 0.28 | 0.82 | R |
AA vs. GG | 0.00, 1.000 | −0.80, 0.468 | 0.72(0.37,1.43) | 0.35 | 0.83 | R |
AA/AG vs. GG | 1.13, 0.260 | −1.57, 0.193 | 0.75(0.43,1.30) | 0.30 | 0.80 | R |
AA vs. AG/GG | 0.38, 0.707 | −0.00, 0.999 | 0.86(0.56,1.30) | 0.47 | 0.77 | R |
Asians (4) | ||||||
A vs. G | 0.89(0.56,1.41) | 0.61 | 0.89 | R | ||
AA vs. GG | 0.85(0.30,2.43) | 0.77 | 0.89 | R | ||
AA/AG vs. GG | 0.94(0.42,2.13) | 0.89 | 0.86 | R | ||
AA vs. AG/GG | 0.83(0.45,1.55) | 0.56 | 0.86 | R | ||
Caucasians (2) | ||||||
A vs. G | 0.75(0.59,0.97) | 0.03 | 0.03 | F | ||
AA vs. GG | 0.52(0.32,0.86) | 0.01 | 0.00 | F | ||
AA/AG vs. GG | 0.49(0.32,0.74) | 0.00 | 0.00 | F | ||
AA vs. AG/GG | 0.90(0.61,1.34) | 0.60 | 0.00 | F |
Abbreviations: CI, confident interval; OR, odd ratio; R, random model; F, fixed model.