Table 3. Three weeks after infection, the effect of chronic lithium treatment was evaluated in a water maze.
| PM−/NaCl,(n = 12)a | PM−/LiCl,(n = 12)a | Pvalueb | PM+/NaCl,(n = 11)a | PM+/LiCl,(n = 8) a | P valueb | |
| Time to reach platform [s] | 8.3(6.0, 13.5) | 9.8(5.7, 15.1) | 0.7279 | 12.4(7.7, 27.4) | 11.8(5.9, 23.8) | 0.1558 |
| Distance moved to reach platform [cm] | 211.0(146.3, 434.9) | 230.8(128.1, 447.4) | 0.8276 | 302.7(196.2, 968.4) | 294.6(176.6, 793.3) | 0.2530 |
In training trials, the treatment had no effect on time and distance to reach the platform on day 4.
a
values are median (25% percentile, 75% percentile);
b
Mann-Whitney test; PM, pneumococcal meningitis.