Table 5. Metabolites with significant treatment (pistachio, water) x time (5 points) interaction effects.

Metabolite	Pre-Suppl	Pre-Exerc	Post-Exerc	1.5-h Post-Exerc	21-h Post-Exerc	Interaction q-Value
raffinose	1	1	7.81*	7.28*	1	<0.001
9,10-DiHOME	1.06	2.96*	5.36*	5.6*	1.66	<0.001
sucrose	0.72	1.73	4.35*	3.49*	1.78	<0.001
glycodeoxycholate	0.87	1.61	4.31*	1.96*	2.18	0.006
2-hydroxydecanoate	1.21	2.58*	3.21*	3.17*	2.27*	<0.001
glycochenodeoxycholate	0.8	1.38	2.68*	1.64*	1.45	0.024
allantoin	1.36	1.13	2.55*	2.08*	1.23	0.016
phenylacetate	0.72	1.74	2.24*	1.8	1.37	0.032
phenylacetylglutamine	0.98	1.64*	2.05*	2.07*	1.53*	0.023
1-oleoylglycerophos-phoethanolamine	1.08	1.01	1.7*	1.62*	0.92	<0.001
2-oleoylglycerophos-phoethanolamine	1.19	1.05	1.69*	1.61*	0.89	0.042
azelate	0.97	0.99	1.64*	1.43*	1.07	<0.001
isobutyrylcarnitine	0.98	1.27	1.63*	1.43*	1.22	0.024
indoleacetate	1.04	1.56*	1.61*	1.53*	1.29	0.015
2-aminooctanoate	1.02	1.55*	1.58*	1.62*	1.45*	0.006
myo-inositol	1.09	1.02	1.4*	1.45*	0.99	0.015
gamma-glutamylleucine	1.03	1.08	1.31*	1.25*	1.07	0.015
gamma-glutamyltyrosine	0.96	1.05	1.2*	1.26*	0.98	0.023
leucine	0.99	1.14*	1.18*	1.14*	1.04	0.014

Values represent the ratio of pistachio-to-water median scaled intensity values at each time point (mean±SE).

* = Q-value 2-way ANOVA contrasts <0.05.