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. 2014 Nov 19;9(11):e113722. doi: 10.1371/journal.pone.0113722

Figure 3. Expression of marker genes of M1 and M2 macrophages.

Figure 3

mRNA levels of the M2 markers CD163 (A), ARG1 (B), IL10 (C), and the M1 marker IL12B (D) in THP-1 and HL60 cells. (E) mRNA levels of the M2 marker TGFB1, the M1 markers TNF, IL6, and NOS2 in THP-1 cells. Cells were treated with vehicle control (Cont), 30 nM 9cRA, or ATRA in the absence or presence of 100 nM 1,25(OH)2D3 (D3) for 72 hours. *, p<0.05; **, p<0.01; ***, p<0.001 (one-way ANOVA followed by Tukey’s multiple comparisons). n.d., not detected.