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. 2014 Nov 24;87:529–539. doi: 10.1016/j.ejmech.2014.09.062

Scheme 2.

Scheme 2

General scheme for assembly of different P23DC analogs. Conditions: a) acetic anhydride; b) acetonitrile:water (1:1), substituted aniline, dodecyl hydrogen sulfate sodium salt, rt; c) trifluoroacetic anhydride, TEA, THF; d) substituted aniline or benzyl amine, THF, rt.