Table 1.

Advantages and Disadvantages of Current Repair Strategies

Reconstruction Strategy	Autologous Grafts	Autologous Free Tissue Flaps	Alloplastic Permanent Prostheses	Alloplastic Synthetic Grafts
Advantages	• Possess endogenous osteoinductive / osteoconductive factors • Consist of relatively simple procedure	• Established as current gold standard • Result in vascularized tissue	• Result in no donor site morbidity • Have capability of fully recapitulating defect geometry	• Result in no donor site morbidity • Are available in different ceramic compositions
Disadvantages	• Result in donor site morbidity • Lack vasculature • Are appropriate only for small defects	• Result in donor site morbidity • Give rise to increased operation room time • Are technically demanding	• Demonstrated to have high risk of infection • Often result in poor soft tissue integration • Carry potential risk of extrusion	• Lack vasculature • Prediction of resorption rates is difficult