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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Integr Biol (Camb). 2014 Dec;6(12):1170–1182. doi: 10.1039/c4ib00086b

Figure 3. Transcription factor targets overexpression in breast cancer human tumors.

Figure 3

Chi-square in log10 scale for AP1, SRF, STATs, E2Fs and YYs families during ErbB2 activation according to the dynamic network (Fig. 2) in ErbB2 positive human breast cancer tumors in comparison with triple negative human breast cancer tumors. Horizontal lines indicate level of significance (p-value≤0.01). Blue bars represent the overexpression of a given TF when considering consensus mammal promoters; red bars represent the overexpression of a given TF when considering just human promoters.