Δldb1-induced activation of early lens, olfactory, and cement gland markers in ectodermal recombinants. A: Schematic of recombinant procedure; Stage 10-11 Δldb1 RNA-injected ectoderm combined with Stage 11-11.5 lineage-labeled ectoderm, cultured to the equivalent of Stages 18-26, processed for in situ hybridization with foxe3, nrl-maf, dlx5, and ag1, and sectioned for analysis. B-C: Expression of foxe3 and lineage labeling of ectoderm, Stage 24. D-E: Expression of nrl-maf and lineage labeling of ectoderm, Stage 26. F-G: Expression of dlx5 and lineage labeling of ectoderm, Stage 18. H-I: Expression of ag1 and lineage labeling of ectoderm, Stage 18. Arrowheads indicate identical locations on each pair of images. Table: Expression of genes in recombinants; markers of the lens, nose, and cement gland are detected in Δldb1-injected recombinants, markers of neural and neural crest tissue are not.