. Author manuscript; available in PMC: 2015 May 2.

Published in final edited form as: J Nucl Med. 2014 May 19;55(7):1047–1053. doi: 10.2967/jnumed.113.136044

TABLE 2.

Univariate Analysis of Relationship Between Tumor Shrinkage at 2 Months and Covariates Evaluated at Tumor Level

Parameter	Median	n	Correlation with tumor volume shrinkage
			P	r ^*
Baseline tumor volume (mL)	20 (1–716)	130	0.078	−0.166
Initial shrinkage (during tracer imaging) (%)	10 (–48 to 47)	130	0.163	0.132
Tracer-predicted mean tumor-absorbed dose (cGy)	248 (80–768)	130	0.002	0.290
Therapy-delivered mean tumor-absorbed dose (cGy)	275 (94–711)	124	0.021	0.222
Therapy-delivered minimum tumor dose (cGy)	130 (2–382)	124	0.078	0.171
Therapy-delivered tumor D99 (cGy)	156 (29–408)	124	0.034	0.204
Therapy-delivered tumor D80 (cGy)	216 (58–481)	124	0.021	0.222
Therapy-delivered equivalent biologic effect	0.87 (0.004–6.57)	124	<0.0001	0.490

Spearman rank correlation was used.

D99 and D80 = absorbed dose received or exceeded by 99% and 80%, respectively.

Data in parentheses are ranges.